A Revision of the International Classification of Retinopathy of Prematurity

Retinopathy of prematurity (ROP) is still a major threat to premature babies' vision, with some cases resulting in irreversible vision loss. The International Categorization of Retinopathy of Prematurity (ICROP), a clinical classification system for acute ROP, was created in 1984 with input from experts from around the world. 

Cryotherapy's efficacy in preventing retinal detachment and vision loss due to ROP was promptly proven in a multicenter clinical trial. 2 Since its inception, ICROP has enhanced clinical care by permitting reliable documenting of ROP, facilitating comparison of serial examinations by numerous doctors, and facilitating consultation with peers.

The ICROP has undergone fine-tuning in the past, most recently in 2005. 3 The ICROP3 classification, which was released this year, was updated to better characterise the disease as it is being managed. 4 ICROP3's primary revisions address concepts added over the last two decades that are thought to influence the outcome or are linked to alterations specific to anti-intravitreal vasculitis injection.

While not as groundbreaking as ICROP's zone, stage, and plus/not retinal vascularity, these additional findings may have a significant impact on the baby's chance of a negative result. ICROP3 will promote clinical data collecting, prompt exploration of the influence of these extra criteria on the course of the disease, and improve communication, just as previous iterations of the classification did.


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