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Showing posts from October, 2021

Longitudinal Changes in Scotopic and Mesopic Macular Function as Assessed with Microperimetry in Patients with Stargardt Disease

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  The Nidek MP1S device was used to measure central 20 ° macular sensitivity under mesopic and scotopic conditions. Mean deviations (MD) from normal value for mesopic macular sensitivity for fovea (within 2 ° eccentricity) and extrafovea (4 ° 10 ° eccentricity) and the MD for scotopic sensitivity for extra fovea were calculated. Linear mixed effects models were used to estimate mesopic and scotopic changes and the mMD was 10.7 dB (p <0.001). Longitudinally, all eyes showed a statistically significant deterioration trend: the rates of foveal mMD and extrafoveal mMD and some were 0.72 (95% CI 0.37 to 1.07), 0.86 (95% CI: 0.58 to 1.14) and 1.12 (95% CI.). : 0.66 to 1.57) dB / year. In STGD1, the loss of scotopic macular function preceded the extrafovea and was faster than the loss of mesopic macular function. Scotopic and mesopic macular sensitivities using microperimetry provide alternative visual function results for STGD1 treatment studies. At baseline, all eyes had a larger sMD and

Surgical outcomes for esotropia in children with high accommodative convergence/accommodation ratio

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To assess whether a high accommodative / accommodative convergence (AC / A) ratio affects surgical outcomes in children with esotropia (ET) and to assess the appropriate target angle of surgical dosing in the presence of a high AC / A ratio. A retrospective review identified patients who suffered a primary bilateral medial rectus (BMR) due to TS. Patients were excluded if the follow-up was ≤ 2 months. Basic demographic information, visual acuity, stereopsy, orientation, and target angles for surgery were collected. High AC / A was defined as a deviation of ≥10 prismatic diopters (Δ)   near compared to distance. Outcome parameters were near and far deviations ≤10Δ within orthophoria and / or postoperative stereopsis. Yates' Continuity Correction, Unpaired T Test, Regression Analysis and one-way ANOVA were used. 103 patients were identified preoperatively, 23 with high AC / A and 80 with normal AC / A. The mean age was 4.0 ± 2.5 years. Surgical success, measured by postoperative orie